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The Encyclopaedic Companion to Medical Statistics, contains a readable accounts of almost 400 statistical topics central to current medical research. Each entry has been written by an individual chosen for both their expertise in the field and their ability to communicate statistical concepts successfully to medical researchers.
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To practice evidence-based medicine, doctors need to understand how research is conducted and be able to critically appraise research evidence. A sound understanding of medical statistics is essential for the correct evaluation of medical research and the appropriate implementation of findings in clinical practice.
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Genetic epidemiology is a very rapidly developing field that has acquired a central role in modern biomedical science. Driven by fast-paced technological advances arising from the sequencing of the human genome, and the rolling-out of these technologies into population-based studies, remarkable advances have occurred recently in our ability to detect genetic polymorphisms which contribute to susceptibility to complex human disease.
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Chronic pain is a major cause of distress, disability, and work loss, and it is becoming increasingly prevalent through the general move towards an ageing population, which impacts dramatically upon society and health care systems worldwide. Due to improvements in health care, it is becoming more common for patients to continue living with long-term illness or disease (rather than these being terminal).
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Although recognised clinically for some time as an important condition that increases risk of ill-health in affected individuals, it is only recently that obesity had been recognised as a population-wide problem that requires preventive action. Obesity is a major contributor to diseases and disability, the associated health costs are enormous and obesity has already reached epidemic proportions in many countries, and incidence is continuing to increase in children and adults.
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International health and aid policies of the past two decades have had a major impact on the delivery of care in low and middle-income countries. This book argues that these policies have often failed to achieve their main aims, and have in fact contributed to restricted access to family medicine and hospital care.
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This book will serve as a road map for students and junior researchers seeking to successfully design, implement, and publicize the results of clinical research. It covers the basic elements of research proposals and implementation including regulatory approvals, continuing regulatory oversight, monitoring patient safety, recruitment, clinical assessments, laboratory assessments, provision of treatment, and on-going quality control.
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